Biomarkers of cytokine release syndrome and neurotoxicity related to CAR-T cell therapy
نویسندگان
چکیده
منابع مشابه
Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel
BACKGROUND Anti-CD19 CAR T cell therapy has demonstrated high response rates in patients with relapsed or refractory (r/r) B cell malignancies but is associated with significant toxicity. Cytokine release syndrome (CRS) is the most significant complication associated with CAR T cell therapy, and it is critical to have a reproducible and easy method to grade CRS after CAR T cell infusions. DIS...
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ژورنال
عنوان ژورنال: Biomarker Research
سال: 2018
ISSN: 2050-7771
DOI: 10.1186/s40364-018-0116-0